Biophotonics / Internet Plenary Lecture

CANCER MARGIN DELINIATION BY AUTOFLUORESCENCE IMAGING UNDER CONDITIONS OF LASER SURGERY

Alexandre Douplik, Erlangen Graduate School in Advanced Optical Technologies, Friedrich-Alexander University, Erlangen, Germany

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ABSTRACT

Cancer Margin Deliniation by Autofluorescence Imaging under Conditions of Laser Surgery

Image modalities such as spectral imaging, particularly fluorescence imaging, narrow band imaging, microendoscopy, chromoendoscopy and chromomicroendoscopy, infrared endoscopy have been successfully applied in clinical practice for surgical navigation or guidance of tumor resection. The main concern of our study is an alteration of the fluorescence cancerous/normal tissue contrast due to changes of tissue optical properties as a result of surgical interventions such as laser surgery application. Obviously, the high power biotissue processing alternates the optical properties of the tissue and this is well described in the literature. We consider in this study how this affects the cancer spot deliniation contrast and what is more important, how eventually to provide a good quality of surgical navigation to control the cancer removal even under conditions of high power effects like coagulation and ablation.

Representing Author:

Alexandre Douplik, Erlangen Graduate School in Advanced Optical Technologies, Friedrich-Alexander University, Head of Clinical Photonics Lab (Erlangen, Germany)

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